Skin Regeneration | Durham
Polynucleotides Durham Cellular Repair, Lasting Skin Transformation
Polynucleotides are one of the most exciting developments in aesthetic medicine in recent years. Not because of clever marketing. Because the results, when used correctly and in the right client, are genuinely impressive.
This is not a hydration treatment. This is not filler. Polynucleotides work at a cellular level to repair, regenerate and rebuild your skin from the inside out. The results build over weeks and they last.
What are polynucleotides?
Polynucleotides, also known as PDRN (polydeoxyribonucleotide), are purified DNA fragments derived from salmon or trout. They have been used in medical settings for decades for their proven ability to stimulate tissue repair and regeneration.
When injected into the skin, polynucleotides trigger fibroblast activity, which is the process responsible for producing collagen and elastin. They also promote new blood vessel formation, improve skin hydration from within, and have a significant anti-inflammatory effect. The result is skin that is structurally improved, not just superficially treated.
At The Aesthetic Surgery | Durham, we use premium, clinically proven polynucleotide products sourced through UK-regulated pharmacies. Treatment is delivered personally by Lee, with a thorough consultation and tailored treatment plan for every client.
Polynucleotides are one of the treatments we are most passionate about at this clinic. Particularly for the under-eye area, where very few treatments actually deliver meaningful results. When used correctly, the transformation can be remarkable.
Skin Boosters
Hyaluronic acid based. Attract and retain water in the skin. Deliver deep hydration and immediate glow. Results visible quickly.
Polynucleotides
DNA fragment based. Stimulate cellular repair and collagen production. Rebuild skin structure from within. Results build progressively over weeks.
Both treatments have their place and for many clients combining the two as part of a structured treatment plan delivers the best overall result. Your consultation will help determine the right approach for your skin.
Treatment areas
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Under-eye area dark circles and crepiness
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Full face skin quality and texture
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Neck and décolletage
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Hands
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Acne scarring and uneven skin tone
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Loss of skin firmness and elasticity
The under-eye area is where polynucleotides genuinely stand apart from other treatments. Dark circles caused by skin thinning, crepiness, fine lines and hollowing all respond well to polynucleotide treatment over a course of sessions. It is one of the most requested treatment areas at The Aesthetic Surgery | Durham.
Who is it suitable for? Polynucleotides work well across a range of skin types, tones and ages. You may be a good candidate if: You have noticed your skin losing firmness, tone or elasticity The under-eye area looks tired, thin or hollow regardless of how much sleep you get Your skin texture is uneven, dull or lacking its former quality You have acne scarring or pigmentation you want to improve You are looking for longer-term skin improvement rather than a quick fix You want to rebuild and protect your skin health proactively Other treatments have not delivered the skin quality results you were hoping for
What to expect
Free consultation
A thorough skin assessment and honest conversation about your concerns and goals. We will assess whether polynucleotides are the right treatment for you and build a plan accordingly.
Treatment
A topical numbing cream is applied before treatment for comfort. The product is injected into the target area using a fine needle technique. Sessions typically take 30 to 45 minutes. Most clients find the treatment very well tolerated.
Initial course
A course of 2 to 3 sessions spaced 2 to 4 weeks apart is recommended for optimal results. The skin continues to improve between sessions as the regenerative process builds.
Maintenance
After completing an initial course, maintenance sessions every 6 to 12 months help sustain and build on results over time. Many clients incorporate polynucleotides as a regular part of their skin health routine.
A course of 2 to 3 sessions is recommended for best results. Full pricing and a tailored treatment plan are discussed at your free consultation.
Frequently asked questions
When will I see results?
Unlike some treatments, polynucleotide results build progressively. Initial improvements in skin quality and hydration can be seen within 2 to 4 weeks of the first session, with more significant results developing over the full treatment course. Results continue to improve for several weeks after the final session.
How long do results last?
Results from a full course typically last 6 to 12 months. Regular maintenance sessions help sustain and build on results over time.
Is it painful?
Topical numbing cream is applied before treatment to minimise discomfort. Most clients describe the sensation as mild. The under-eye area can be more sensitive but is very well tolerated by the vast majority of clients.
Is there any downtime?
There is no significant downtime. Some mild redness, swelling or small bumps at injection sites is normal immediately after treatment and typically resolves within a few hours to a day. Most clients return to normal activities the same day.
Are polynucleotides safe for all skin types?
Polynucleotides are suitable for all skin tones and types. They are well tolerated and have an excellent safety profile. A full medical history and skin assessment at your consultation will confirm suitability.
Can polynucleotides be combined with other treatments?
Yes. Polynucleotides combine particularly well with skin boosters, dermal filler and anti-wrinkle treatment as part of a comprehensive treatment plan. Combining treatments often delivers significantly better results than any single treatment alone.
Is there a difference between polynucleotide brands?
Yes. Product quality, concentration and formulation vary between brands. At The Aesthetic Surgery | Durham we use only premium, clinically validated products sourced through UK-regulated pharmacies. The product used will always be discussed at your consultation.
30 min